@Shalaw,
It would be helpful for those answering the question to understand what you mean by "estranged in essence." Estrangement is generally a term used by some Existentialists, for example, for the Self's condition of separation from both the world and oneself, or in Heidegger's case, perhaps from being. Rather than forcing the concept, if this is what is meant, into the thinking of Aristotle to Kant, it might be better to ask about Hegel or Marx.