@Didymos Thomas,
I'm with Victor on this issue. I've done the must-go-out-Friday-and-Saturday lifestyle. Part of that was a) being young, and b) working Monday-to-Friday. Friday night out was a release from a week of work. Saturday was usually a more tempered version of Friday, a proper time to catch up. We drank less because we were still a bit hungover from Friday.
Now not only do I not do it, I don't really see the appeal. I suppose I've reached the age where I've shrugged off friends that were superficial enough to rely heavily on partying and have settled to have fewer, closer relationships. These relationships generally have no schedule - a Tuesday is as good as a Friday.
But things slow down anyway. Such friends get jobs elsewhere, and you tend to see them every month rather than every week. It makes the get togethers too special to get blinded drunk and not remember anything.
But also I don't work 9-5, Mon-Fri anymore. I keep my own hours so never need that Friday night release.
Like Sara, I sometimes walk past a club and miss the old times, but this is just nostalgia. It doesn't work anymore. I'd have to regress and I don't want to. I still go out and get hammered from time to time, just not habitually. I think time is too precious to a) not remember it, and b) have hangovers. The benefits of sharing a well prepared meal with friends seem enormous... and then you know you've grown old.